African Journal of Paediatric Surgery

LETTER TO THE EDITOR
Year
: 2016  |  Volume : 13  |  Issue : 3  |  Page : 158-

Visceral basidiobolomycosis


Beuy Joob1, Viroj Wiwanitkit2,  
1 Sanitation 1 Medical Academic Center, Bangkok, Thailand
2 Tropical Medicine, Hainan Medical University, Haikou, Hainan, China

Correspondence Address:
Beuy Joob
Sanitation 1 Medical Academic Center, Bangkok
Thailand




How to cite this article:
Joob B, Wiwanitkit V. Visceral basidiobolomycosis.Afr J Paediatr Surg 2016;13:158-158


How to cite this URL:
Joob B, Wiwanitkit V. Visceral basidiobolomycosis. Afr J Paediatr Surg [serial online] 2016 [cited 2019 Sep 15 ];13:158-158
Available from: http://www.afrjpaedsurg.org/text.asp?2016/13/3/158/187827


Full Text

Sir,

The report on 'visceral basidiobolomycosis (VB)' is very interesting. [1] Mandhan et al. concluded that 'VB is rare and aggressive, fungal disease in a paediatric population of tropical and subtropical regions', [1] and 'it usually presents atypically; hence, it should be included as one of the differential diagnoses in children with abdominal sepsis'. [1] In fact, VB is a deadly fungal infection and diagnosis is usually difficult. Mandhan et al. mentioned for the requirement of surgical biopsy to yield diagnosis. [1] It should be noted that VB is usually overlooked. El-Shabrawi and Kamal noted that 'diagnosis requires a high index of suspicion in the differential diagnosis of patients with fever, abdominal pain with mass and eosinophilia'. [2] An important concern is on the diagnosis. The confirmation is usually based on specific fungal culture of the derived surgical specimen, which might not be available in some settings. In fact, there are also other alternative diagnostic tools. In cases with suspicious findings (fever, abdominal mass and eosinophilia), the immunological test might be helpful. Immunodiffusion test is the best example. [3],[4] Imwidthaya and Srimuang noted that 'this test was found to be practical, sensitive and specific'. [3] Finally, it should also be noted that polymerase chain reaction for diagnosis was also recently developed. [5]

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Conflicts of interest

There are no conflicts of interest.

References

1Mandhan P, Hassan KO, Samaan SM, Ali MJ. Visceral basidiobolomycosis: An overlooked infection in immunocompetent children. Afr J Paediatr Surg 2015;12:193-6.
2El-Shabrawi MH, Kamal NM. Gastrointestinal basidiobolomycosis in children: An overlooked emerging infection? J Med Microbiol 2011;60(Pt 7):871-80.
3Imwidthaya P, Srimuang S. Immunodiffusion test for diagnosing basidiobolomycosis. Mycopathologia 1992;118:127-31.
4Kaufman L, Mendoza L, Standard PG. Immunodiffusion test for serodiagnosing subcutaneous zygomycosis. J Clin Microbiol 1990;28:1887-90.
5Gómez-Muñoz MT, Fernández-Barredo S, Martínez-Díaz RA, Pérez-Gracia MT, Ponce-Gordo F. Development of a specific polymerase chain reaction assay for the detection of Basidiobolus. Mycologia 2012;104:585-91.