African Journal of Paediatric Surgery About APSON | PAPSA  
Home About us Editorial Board Current issue Search Archives Ahead Of Print Subscribe Instructions Submission Contact Login 
Users Online: 114Print this page  Email this page Bookmark this page Small font size Default font size Increase font size 
 
ORIGINAL ARTICLE
Year : 2004  |  Volume : 1  |  Issue : 1  |  Page : 16-19

Epidemiology of neural tube defects in North Central Nigeria


1 Department of Surgery, Jos University Teaching Hospital, Jos, India
2 Department of Anaesthesia, Jos University Teaching Hospital, Jos, India
3 Department of Anaesthesia, Bayero University, Kano, India

Correspondence Address:
A F Uba
Paediatric Surgery Unit, Department of Surgery, Jos University Teaching Hospital, P.M.B. 2076, Jos
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions

Background. Neural tube defects (NTDs) are associated with high childhood morbidity worldwide. We wanted to know the pattern and the possible aetiological factors responsible for this anomaly in northcentral Nigeria. Patients and Methods. The clinical records of all children with NTD admitted at JUTH between 1986 and 2003 were reviewed and the data analyzed for age, gender and antenatal care, incidence, type and location of lesion. Results. There were 284 patients (144 males and 140 females). The incidence of NTD was 0.5/1000 live births and 1.9% of all admissions. The Hausa / Fulani ethnic group constituted the highest proportion. In 165 (58%) patients, the mothers had received antenatal care; however, the antenatal care generally started late in pregnancy. Spina bifida constituted 97% of the total NTDs, 79.6% of which were meningomyeloceles. The sites mostly affected were the lumbosacral and the thoracolumbar regions in 55.8% and 31.9% of cases, respectively. Hydrocephalus was the most common complication occurring in 194 (68.3%) patients. Among those patients presenting with myelomeningocele, 95 (42%) had ruptured sacs, while in 62 (27.4%) the sacs were ulcerated and locally infected; 15 (6.6%) patients had meningitis while 16 (7.1%) had septicemia. Conclusion. The most common type of NTD in this study was lumbosacral myelomeningocele, the majority of which were complicated at presentation. Consanguinity marriage and delayed or absence of antenatal care appear to be important aetiological factors.


[PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1169    
    Printed88    
    Emailed0    
    PDF Downloaded102    
    Comments [Add]    

Recommend this journal